I'm new to this forum but have been playing Ant Buster for quite awhile now. I don't cheat because, well, what's the point? It's just a fun game and an enjoyable way to pass some time. In any case, I have been reading some of the discussions on strategies, what are the best weapons to deploy, etc., and I have come to my own conclusions after trying various methods and combinations. I strongly believe in the following:
I support the primary hole defense, minimal cake defense startegy. By strongly defending the hole, you make the ants pass you twice, coming out and then going back in with cake.
1) Use a single ice cannon near the hole, and also one near the cake. It's best to slow these suckers down so other weapons can blast em. However, I don't like to use multiple ice cannons since they have little destructive force.
2) I prefer to use a single poison spray near the hole. It helps destroy ants quite easily at earlier levels (allowing me to build up other force) and once upgraded, the spray helps to whittle away ants power and disorient them a bit, causing them to often take some strange, more time consuming paths when they return with slices of cake and make them easier to destroy.
3) Other than that, I only use missle launchers. Though they are slow to fire, they are able to target cake-carrying ants, and they carry the greatest destructive power which becomes much needed at higher levels. Missle launchers don't miss their targets, unless their missles are blocked by other ants who happen to get in the way.
I have tried all other weapons in various combinations and note that they often shoot behind their targets, even with ants that have been significantly slowed by the ice cannons, or have other major shortcomings, usually lack of destructive power. These have all been quite frustrating and in the end, ineffective.
I usually try to attain 11 or 12 total cannons in my defense. As for which ants I will choose to target, this depends, but usually it will be the cake bearers who are closest to reaching the hole (obvious) or the highest powered ant on the board. However, if I am nearing a money level where I can purchse another needed cannon, I may target lower powered ants to help achieve the needed money to buy the additional cannon and deploy it more quickly.
I attach a screen shot from one of my more recent games where I reached level 104. My all time high is level 105.
I hope this message is of interest and some help to those of you who may not have tried these strategies yet and are eager to improve your scores.